have ever had an allergic reaction to aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen. have or have had stomach ulcers, bleeding in the stomach or intestines, or a hole in your stomach. have high blood pressure. have severe liver or kidney failure.

Adults—At first, 1000 milligrams (mg) (taken as two 500 mg tablets) once a day. Some patients may need 1500 mg (taken as two 750 mg or three 500 mg tablets) per day, for a limited period. However, the dose is usually not more than 1000 mg per day. Children—Use and dose must be determined by your doctor.

Taking naproxen in occasional doses or short courses (2 or 3 days) is safe.